Figure 2.

The histological integrity of the samples (HE stain; magnification, ×100). (A1,A2) High quality. Histological cores are present, with tumor cells arranged in a glandular pattern, showing partial gland fusion and prominent malignant accompanied by significant stromal reaction, diagnosed as pancreatic carcinoma (A1,A2 are derived from the same patient). (B1,B2) Low quality. Atypical glands are distributed sporadically with rupture, and no fibrous stroma is observed; however, the presence of malignant cells allows for a diagnosis of pancreatic carcinoma based on cellular morphology (B1,B2 are derived from the same patient). (C1,C2) Insufficient material. The specimen predominantly shows hemorrhage, with only a few normal glandular epithelial cells present, preventing a definitive diagnosis (C1,C2 are derived from the same patient).