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. 2024 Dec 6;15:1503154. doi: 10.3389/fphar.2024.1503154

TABLE 1.

Overview of Enfortumab vedotin and Erdafitinib.

Drug name Chemical name Structure Main treatment First marketed year
Enfortumab vedotin Anti-Nectin 4 ADC ASG-22CE C6468H10012N1720O2038S44 Advanced/metastatic urothelial carcinoma, particularly in patients previously treated with platinum-based chemotherapy and PD-1/PD-L1 inhibitors 2019
Erdafitinib N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine C25H30N6O2 Advanced/metastatic urothelial carcinoma with FGFR3 or FGFR2 genetic alterations 2019