TABLE 1.
Overview of Enfortumab vedotin and Erdafitinib.
Drug name | Chemical name | Structure | Main treatment | First marketed year |
---|---|---|---|---|
Enfortumab vedotin | Anti-Nectin 4 ADC ASG-22CE | C6468H10012N1720O2038S44 | Advanced/metastatic urothelial carcinoma, particularly in patients previously treated with platinum-based chemotherapy and PD-1/PD-L1 inhibitors | 2019 |
Erdafitinib | N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine | C25H30N6O2 | Advanced/metastatic urothelial carcinoma with FGFR3 or FGFR2 genetic alterations | 2019 |