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. 2024 Dec 6;15:1449975. doi: 10.3389/fimmu.2024.1449975

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Copyright © 2024 Liu, Li, Lei, Zhou, Huang, Li, Zhang, Jiang, Wu, Zheng, Ma and Tang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional exploration of PGK1 in sepsis. (A) Volcano plot and (B) Heatmap for differentially expressed genes (DEGs) between high_PGK1 and low_PGK1 sepsis patients. (C, D) Gene set enrichment analysis (GSEA) and Gene Set Variation Analysis (GSVA) for the signaling pathways enrichment in different groups. (E) Volcano plot for PGK1-coexpressed genes in sepsis. (F) Correlation heatmap of top 20 PGK1-coexpressed genes, the pie size indicates the degree of correlation. Circos plot for GO (G) and KEGG (H) function enrichment analysis.