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. 2024 Dec 19;9:244. doi: 10.1038/s41541-024-01036-2

Table 2.

Significant Logistic regression of mortality on dose candidate. CoP: [(Est/SE)/(P-Value)]

Criteria NiVB ELISA Titer on Study Day 21 NiVM ELISA Titer on Study Day 21 NiVB FRNT50 NiVM FRNT50
Treatment (Dose) affecting endpoint (2.16)/(0.032) (2.16)/(0.032) (2.16)/(0.032) (2.16)/(0.032)
Treatment (Dose) affecting CoP (5.12)/( < 0.0001) (5.15)/( < 0.0001) (6.21)/( < 0.0001) (7.48)/(0.0001)
CoP affecting endpoint (2.17)/(0.027) (2.00)/(0.046) (2.23)/(0.026) (2.37)/(0.018)
Treatment offers no more information than CoPa 0.028/0.85 0.10/0.37 0.06/0.14 0.06/0.48

a.- Summary P-Values for Correlate of Protection (CoP) and Dose (CoP/Dose).