Table 2.
Significant Logistic regression of mortality on dose candidate. CoP: [(Est/SE)/(P-Value)]
| Criteria | NiVB ELISA Titer on Study Day 21 | NiVM ELISA Titer on Study Day 21 | NiVB FRNT50 | NiVM FRNT50 |
|---|---|---|---|---|
| Treatment (Dose) affecting endpoint | (2.16)/(0.032) | (2.16)/(0.032) | (2.16)/(0.032) | (2.16)/(0.032) |
| Treatment (Dose) affecting CoP | (5.12)/( < 0.0001) | (5.15)/( < 0.0001) | (6.21)/( < 0.0001) | (7.48)/(0.0001) |
| CoP affecting endpoint | (2.17)/(0.027) | (2.00)/(0.046) | (2.23)/(0.026) | (2.37)/(0.018) |
| Treatment offers no more information than CoPa | 0.028/0.85 | 0.10/0.37 | 0.06/0.14 | 0.06/0.48 |
a.- Summary P-Values for Correlate of Protection (CoP) and Dose (CoP/Dose).