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. 2024 Dec 19;7:302. doi: 10.1038/s42004-024-01392-z

Fig. 4. IEDDA reaction between tetrazines 2a-c and TCO.

Fig. 4

a Reaction scheme; b table with half-life of 4,5-tautomers 17a–c in organic solution at 20 °C; c 1H-NMR spectra (CDCl3) of reaction of 2a and TCO, resulting in 4,5-tautomer 17a, and its tautomerization to 1,4-tautomer 18a (legend: + 17a; * 18a).