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. 2024 Dec 19;7(12):e2450489. doi: 10.1001/jamanetworkopen.2024.50489

Table 3. Factors Associated With Goals and Timinga.

Characteristic Palliative goals Nonpalliative goals
Initial Middle Late
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Age at death, y
12-24 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
25-39 0.79 (0.69-0.90) <.001 1.08 (0.91-1.30) .40 1.33 (1.09-1.61) <.01 1.34 (1.09-1.65) <.01
Year of death 1.07 (1.07-1.07) <.001 1.11 (1.11-1.11) <.001 1.14 (1.13-1.14) <.001 1.13 (1.13-1.13) <.001
Sex
Female 1 [Reference] .50 1 [Reference] .40 1 [Reference] .20 1 [Reference] .06
Male 0.96 (0.83-1.10) 1.08 (0.90-1.29) 1.12 (0.95-1.33) 1.20 (0.99-1.46)
Race
Asian 1.75 (1.61-1.91) <.001 1.38 (1.26-1.51) <.001 0.82 (0.67-1.00) .05 0.77 (0.69-0.85) <.001
Black or African American 0.61 (0.59-0.62) <.001 0.75 (0.72-0.78) <.001 0.69 (0.58-0.83) <.001 0.76 (0.68-0.85) <.001
White 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
Other race or not documentedb 1.39 (1.19-1.63) <.001 1.23 (1.05-1.44) .01 0.81 (0.65-1.02) .07 1.26 (1.05-1.52) .01
Ethnicity
Hispanic or Latino 0.48 (0.42-0.55) <.001 0.53 (0.45-0.61) <.001 0.67 (0.56-0.81) <.001 0.56 (0.47-0.66) <.001
Not Hispanic or Latino 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
Not documented 0.90 (0.81-1.00) .04 0.71 (0.64-0.78) <.001 0.89 (0.75-1.06) .20 1.18 (1.02-1.36) .02
Cancer type
Brain 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA
Hematologic cancer 0.29 (0.27-0.31) <.001 0.25 (0.23-0.28) <.001 0.52 (0.47-0.58) <.001 0.88 (0.78-1.00) .06
Solid tumor 0.49 (0.44-0.56) <.001 0.58 (0.50-0.67) <.001 0.66 (0.58-0.77) <.001 0.84 (0.73-0.97) .02

Abbreviations: NA, not applicable; OR, odds ratio.

a

Multinomial logistic regression model adjusted for site, relative to adolescent and young adult patients with no documented discussion about goals of care.

b

Other races included: American Indian or Alaska Native, Asian Indian, Native Hawaiian or Other Pacific Islander, more than 1 race, decline to state, or unknown.