Table 1.
Characteristics of the Patients
| Characteristic | Exercise Classification1 |
||
|---|---|---|---|
| Overall | Non-Exercisers | Exercisers | |
| No. of patients – (row %) | 11,480 (100) | 7,106 (62) | 4,374 (38) |
| Estimated minutes of moderate exercise per week – median (IQR) | 44 (8, 100) | 19 (8, 61) | 100 (61, 180) |
| Unknown | 38 | 0 | 38 |
| Estimated minutes of strenuous exercise per week – median (IQR) | 19 (8, 86) | 8 (8, 19) | 100 (61, 155) |
| Unknown | 17 | 0 | 17 |
| Age at exercise survey completion – median (IQR) | 73 (68, 77) | 73 (69, 78) | 72 (68, 76) |
| Age at diagnosis – median (IQR) | 68 (64, 72) | 68 (64, 73) | 67 (63, 71) |
| Interval between diagnosis and survey completion (years) – median (IQR) | 4.50 (2.09, 6.98) | 4.36 (2.02, 6.92) | 4.69 (2.25, 7.07) |
| PLCO Intervention Arm | 6,030 (53) | 3,691 (52) | 2,339 (53) |
| Female – no. (%) | 4,567 (40) | 2,992 (42) | 1,575 (36) |
| Race/ethnicity – no. (%) | |||
| Non-Hispanic white | 10,461 (93) | 6,467 (93) | 3,994 (93) |
| Other group | 807 (7.2) | 495 (7.1) | 312 (7.2) |
| Missing | 212 | 144 | 68 |
| Body mass index – kg/m2 | |||
| 0–18.5 | 55 (0.5) | 41 (0.6) | 14 (0.3) |
| >18.5–24.9 | 3,716 (33) | 2,100 (31) | 1,616 (38) |
| >25–29.9 | 4,998 (45) | 3,105 (45) | 1,893 (45) |
| >30 | 2,350 (21) | 1,623 (24) | 727 (17) |
| Unknown | 361 | 237 | 124 |
| Smoking, pack-years – median (IQR) | 5 (0, 34) | 7 (0, 37) | 3 (0, 26) |
| Unknown | 327 | 224 | 103 |
| Primary diagnosis – no. (%) | |||
| Prostate | 4,261 (37) | 2,452 (35) | 1,809 (41) |
| Breast (female) | 2,276 (20) | 1,435 (20) | 841 (19) |
| Colon | 872 (7.6) | 598 (8.4) | 274 (6.3) |
| Hematopoietic | 855 (7.4) | 565 (8.0) | 290 (6.6) |
| Melanoma | 773 (6.7) | 423 (6.0) | 350 (8.0) |
| Bladder | 535 (4.7) | 348 (4.9) | 187 (4.3) |
| Lung | 391 (3.4) | 278 (3.9) | 113 (2.6) |
| Endometrial | 374 (3.3) | 244 (3.4) | 130 (3.0) |
| Renal | 240 (2.1) | 165 (2.3) | 75 (1.7) |
| Head and neck | 204 (1.8) | 133 (1.9) | 71 (1.6) |
| Ovarian | 112 (1.0) | 74 (1.0) | 38 (0.9) |
| Thyroid | 106 (0.9) | 64 (0.9) | 42 (1.0) |
| Upper Gastrointestinal | 94 (0.8) | 62 (0.9) | 32 (0.7) |
| Pancreas | 36 (0.3) | 30 (0.4) | 6 (0.1) |
| Male Breast | 14 (0.1) | 9 (0.1) | 5 (0.1) |
| Biliary | 12 (0.1) | 10 (0.1) | 2 (<0.1) |
| Glioma | 12 (0.1) | 8 (0.1) | 4 (<0.1) |
| Liver | 9 (<0.1) | 7 (<0.1) | 2 (<0.1) |
| Other2 | 304 (2.6) | 201 (2.8) | 103 (2.4) |
| Cancer stage at diagnosis – no. (%) | |||
| In situ | 926 (8.1) | 522 (7.3) | 404 (9.2) |
| Localized | 6,738 (59) | 4,076 (57) | 2,662 (61) |
| Regional | 1,463 (13) | 953 (13) | 510 (12) |
| Distant | 464 (4.0) | 306 (4.3) | 158 (3.6) |
| Unknown | 1,889 (16) | 1,249 (18) | 640 (15) |
| History of chronic conditions– no. (%) | |||
| Arthritis | 3,976 (36) | 2,614 (38) | 1,362 (32) |
| Unknown | 289 | 187 | 102 |
| Chronic bronchitis | 449 (4.0) | 317 (4.6) | 132 (3.1) |
| Unknown | 287 | 187 | 100 |
| Colon-related comorbidity (ulcerative colitis, Crohn’s disease, Gardner’s syndrome, or familial polyposis) | 148 (1.3) | 98 (1.4) | 50 (1.2) |
| Unknown | 313 | 202 | 111 |
| Diabetes | 640 (5.7) | 460 (6.6) | 180 (4.2) |
| Unknown | 282 | 183 | 99 |
| Diverticulitis/diverticulosis | 830 (7.4) | 530 (7.7) | 300 (7.0) |
| Unknown | 286 | 188 | 98 |
| Emphysema | 249 (2.2) | 188 (2.7) | 61 (1.4) |
| Unknown | 283 | 185 | 98 |
| Gallbladder stones or inflammation | 1,203 (11) | 819 (12) | 384 (9.0) |
| Unknown | 289 | 190 | 99 |
| Coronary heart disease or history of heart attack | 916 (8.2) | 617 (8.9) | 299 (7.0) |
| Unknown | 288 | 186 | 102 |
| Hypertension | 3,636 (32) | 2,409 (35) | 1,227 (29) |
| Unknown | 279 | 181 | 98 |
| Liver-related co-morbidity (hepatitis or cirrhosis) | 416 (3.7) | 267 (3.9) | 149 (3.5) |
| Unknown | 294 | 189 | 105 |
| Osteoporosis | 422 (3.8) | 308 (4.5) | 114 (2.7) |
| Unknown | 302 | 194 | 108 |
| Stroke | 205 (1.8) | 144 (2.1) | 61 (1.4) |
| Unknown | 279 | 182 | 97 |
Definitions.
1
Exercisers: moderate-intensity exercise >=4 days per week, with each session, on average, >=30 minutes in duration and/or strenuous-intensity exercise >=2 days per week, with each session, on average, >=20 minutes in duration; and (2) Non-exercisers: any exercise below the criteria for meeting national guidelines, including patients reporting 0 days of exercise per week
2
Other cancers include any other cancer site not listed.