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. 2024 Dec 5;11:1429993. doi: 10.3389/fcvm.2024.1429993

Table 3.

Associations of remnant cholesterol and triglyceride-glucose index with stroke risk stratified by different factorsa.

Subgroup RC with stroke risk TyG index with stroke risk
HR (95% CI) P for interaction HR (95% CI) P for interaction
Age, years 0.423 0.589
 <60 1.09 (1.00–1.19) 1.12 (1.00–1.25)
 ≥60 1.07 (0.98–1.18) 1.15 (1.03–1.28)
Gender 0.265 0.255
 Male 1.11 (1.02–1.21) 1.17 (1.05–1.30)
 Female 1.06 (0.97–1.16) 1.10 (0.98–1.23)
Marital status 0.528 0.368
 Married 1.09 (1.02–1.17) 1.14 (1.05–1.24)
 Other 1.08 (0.91–1.28) 1.13 (0.93–1.38)
Residence 0.332 0.573
 Urban 1.13 (1.03–1.24) 1.17 (1.03–1.33)
 Rural 1.06 (0.98–1.16) 1.13 (1.02–1.24)
Education level 0.615 0.553
 No formal education 1.07 (0.95–1.20) 1.18 (1.01–1.36)
 Primary school 1.05 (0.94–1.17) 1.09 (0.97–1.23)
 Middle or high school 1.12 (1.01–1.25) 1.18 (1.01–1.36)
 College or above 1.09 (0.79–1.50) 0.95 (0.61–1.49)
Body mass index, kg/m2 0.578 0.505
 <18.5 0.67 (0.31–1.43) 1.13 (0.66–1.94)
 18.5–23.9 1.09 (0.98–1.22) 1.19 (1.06–1.33)
 24.0–27.9 1.04 (0.93–1.15) 1.03 (0.90–1.18)
 ≥28.0 1.12 (1.00–1.25) 1.17 (0.99–1.38)
Smoking status 0.959 0.943
 Never 1.10 (1.02–1.20) 1.17 (1.05–1.29)
 Former 1.07 (0.89–1.29) 1.17 (0.93–1.47)
 Current 1.07 (0.95–1.21) 1.08 (0.94–1.24)
Drinking status 0.069 0.079
 Never 1.13 (1.04–1.22) 1.18 (1.06–1.31)
 Former 0.87 (0.66–1.13) 0.92 (0.70–1.21)
 Current 1.08 (0.97–1.20) 1.16 (1.02–1.32)
Diabetes 0.064 0.208
 No 1.06 (0.99–1.14) 1.12 (1.03–1.22)
 Yes 1.26 (1.09–1.46) 1.34 (1.06–1.68)
Hypertension 0.927 0.897
 No 1.09 (0.96–1.24) 1.14 (1.00–1.31)
 Yes 1.09 (1.01–1.17) 1.14 (1.04–1.25)
Heart disease 0.508 0.140
 No 1.10 (1.02–1.17) 1.17 (1.08–1.28)
 Yes 1.06 (0.92–1.22) 1.02 (0.86–1.21)
Dyslipidemia 0.706 0.745
 No 1.08 (1.00–1.17) 1.17 (1.07–1.27)
 Yes 1.10 (0.98–1.23) 1.05 (0.89–1.25)
Kidney disease 0.643 0.697
 No 1.09 (1.02–1.16) 1.15 (1.06–1.24)
 Yes 1.13 (0.88–1.44) 1.07 (0.77–1.47)
a

All models were adjusted for age, gender, marital status, residence, education level, body mass index, smoking status, drinking status, diabetes, hypertension, heart disease, dyslipidemia, kidney disease, history of medication use for diabetes, history of medication use for hypertension, history of medication use for dyslipidemia, systole blood pressure, diastolic blood pressure, HbA1c, hsCRP, and eGFR.