Table 4.
Associations of triglyceride-glucose index and remnant cholesterol with stroke risk stratified by different factors.
| Subgroup | β (95% CI)a | ||
|---|---|---|---|
| Total effects | Direct effects | Mediated effects | |
| Age, years | |||
| <60 | −0.16 (−0.23 to −0.10) | −0.11 (−0.22 to 0.10) | −0.05 (−0.21 to 0.02) |
| ≥60 | −0.13 (−0.24 to −0.06) | 0.04 (−0.09 to 0.24) | −0.17 (−0.31 to −0.12) |
| Gender | |||
| Male | −0.28 (−0.40 to −0.17) | −0.07 (−0.23 to 0.24) | −0.21 (−0.43 to −0.11) |
| Female | −0.08 (−0.15 to −0.04) | −0.03 (−0.12 to 0.11) | −0.05 (−0.16 to −0.01) |
| Marital status | |||
| Married | −0.15 (−0.22 to −0.10) | −0.04 (−0.13 to 0.12) | −0.12 (−0.23 to −0.07) |
| Other | −0.20 (−0.39 to −0.04) | −0.11 (−0.37 to 0.31) | −0.09 (−0.38 to 0.03) |
| Residence | |||
| Urban | −0.25 (−0.36 to −0.14) | −0.19 (−0.35 to 0.09) | −0.05 (−0.26 to 0.06) |
| Rural | −0.12 (−0.20 to −0.06) | 0.03 (−0.09 to 0.20) | −0.15 (−0.27 to −0.10) |
| Education level | |||
| No formal education | −0.06 (−0.21 to 0.15) | 0.22 (−0.10 to 0.59) | −0.29 (−0.46 to −0.04) |
| Primary school | −0.02 (−0.12 to 0.13) | 0.11 (−0.10 to 0.38) | −0.13 (−0.26 to 0.04) |
| Middle or high school | −0.12 (−0.23 to 0.02) | −0.04 (−0.26 to 0.25) | −0.08 (−0.25 to 0.15) |
| Body mass index, kg/m2 | |||
| 18.5–23.9 | −0.09 (−0.22 to 0.11) | 0.21 (−0.09 to 0.54) | −0.30 (−0.45 to −0.08) |
| 24.0–27.9 | −0.00 (−0.11 to 0.16) | −0.01 (−0.27 to 0.30) | 0.01 (−0.16 to 0.22) |
| ≥28.0 | −0.09 (−0.16 to 0.03) | −0.06 (−0.26 to 0.18) | −0.03 (−0.16 to 0.15) |
| Smoking status | |||
| Never | −0.11 (−0.15 to −0.03) | 0.03 (−0.07 to 0.13) | −0.14 (−0.25 to −0.04) |
| Former | −0.13 (−0.41 to 0.27) | 0.16 (−0.32 to 0.59) | −0.28 (−0.69 to 0.12) |
| Current | −0.09 (−0.25 to 0.12) | 0.03 (−0.29 to 0.33) | −0.12 (−0.40 to 0.15) |
| Drinking status | |||
| Never | −0.17 (−0.23 to −0.06) | −0.03 (−0.16 to 0.10) | −0.13 (−0.28 to −0.00) |
| Former | 0.27 (0.07 to 0.60) | 0.38 (−0.03 to 0.74) | −0.11 (−0.44 to 0.23) |
| Current | −0.10 (−0.20 to 0.04) | 0.13 (−0.09 to 0.35) | −0.23 (−0.44 to −0.04) |
| Hypertension | |||
| No | −0.08 (−0.17 to 0.04) | 0.06 (−0.12 to 0.26) | −0.14 (−0.34 to 0.02) |
| Yes | −0.15 (−0.22 to −0.07) | −0.05 (−0.15 to 0.13) | −0.10 (−0.22 to −0.06) |
| Without heart disease | −0.16 (−0.23 to −0.09) | 0.01 (−0.09 to 0.18) | −0.18 (−0.29 to −0.13) |
| Without diabetes | −0.11 (−0.18 to −0.04) | 0.04 (−0.06 to 0.22) | −0.15 (−0.27 to −0.11) |
| Without dyslipidemia | −0.15 (−0.22 to −0.07) | 0.07 (−0.03 to 0.25) | −0.22 (−0.34 to −0.18) |
| Without kidney disease | −0.15 (−0.21 to −0.08) | −0.02 (−0.10 to 0.14) | −0.13 (−0.24 to −0.09) |
CI, confidence interval.
a
Adjusted for age, gender, marital status, residence, education level, body mass index, smoking status, drinking status, diabetes, hypertension, heart disease, dyslipidemia, kidney disease, history of medication use for diabetes, history of medication use for hypertension, history of medication use for dyslipidemia, systole blood pressure, diastolic blood pressure, HbA1c, hsCRP, and eGFR. However, the stratification variable was not included.