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. 2025 Jan 1;16(1):183–200. doi: 10.7150/jca.102180

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Functional enrichment analysis of genes associated with risk-score groups in EAC. (A) Volcano plot illustrating differentially expressed genes between high- and low-risk groups. (B) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. (C) Gene Ontology (GO) analysis for biological processes, molecular functions, and cellular components. (D, E) Ridge plot demonstrating the expression distribution across KEGG (D) and HALLMARK (E) pathways as analyzed by Gene Set Enrichment Analysis (GSEA). (F-H) Gene Set Enrichment Analysis (GSEA) reveals significant associations of the high-risk group with lipid metabolism-related processes.