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. 2024 Dec 19;19:859. doi: 10.1186/s13018-024-05343-1

Table 1.

Summary of motor function recovery at 20 weeks

Group I Group II Group III Group IV Group V p-value
Medication after allograft autograft(control) Cryopreserved allograft Cold preserved allograft Cryopreserved allograft + FK506 (0.1 mg/kg) Cold preserved allograft + FK506 (0.1 mg/kg)
No. of animals tested 12 11 13 13 11
Animal weight
Initial weight (g) 341 ± 13.35 339 ± 26.4 327 ± 11.1 329 ± 17.6 338 ± 25.1 p = 0.132
Final weight (g) 521 ± 28.4 543 ± 29.1 537 ± 19.2 486 ± 25.1 488 ± 19.1 p = 0.011
Ankle angle
Maximum passive plantar flexion angle (°) 127 ± 13.0 128 ± 8.5 134 ± 12.7 138 ± 6.5 137 ± 9.8 p = 0.070
% of contralateral side 86.1 ± 8.67 87.2 ± 6.23 90.3 ± 5.91 96.5 ± 7.26 96.2 ± 5.32 p < 0.001
CMAP
Amplitude (mV) 16.0 ± 5.24 15.7 ± 5.51 18.9 ± 5.66 14.9 ± 4.08 18.9 ± 5.07 p = 0.064
% of contralateral side 63.3 ± 23.67 59.9 ± 17.75 55.3 ± 14.89 61.6 ± 17.75 61.0 ± 15.24 p = 0.082
MITF
Tibialis anterior muscle force (g) 691.9 ± 115.11 609.0 ± 64.57 719.0 ± 111.16 690.8 ± 111.16 682.0 ± 174.59 p = 0.020
% of contralateral side 60.9 ± 17.91 60.4 ± 16.68 60.2 ± 21.29 63.7 ± 19.21 67.1 ± 19.77 p = 0.148
Wet muscle weight
Tibialis anterior muscle force (g) 0.62 ± 0.063 0.62 ± 0.050 0.597 ± 0.058 0.66 ± 0.037 0.593 ± 0.064 p = 0.022
% of contralateral side 72.1 ± 6.13 72.5 ± 6.24 69.3 ± 6.53 80.5 ± 6.58 79.0 ± 8.75 p = 0.001