Table 2.
Comparison of laboratory findings between pediatric patients infected with influenza A before, during and after COVID-19 epidemic
| Laboratory findings | Before the pandemic (n = 340) | During the pandemic (n = 196) | After the pandemic (n = 349) | P-value |
|---|---|---|---|---|
| WBC (×109/L) | ||||
| Reduced | 41/222 (18.5) | 23/129 (17.8) | 72/204 (35.3) | < 0.001 |
| Elevated | 16/222 (7.2) | 0/129 (0.0) | 13/204 (6.4) | < 0.001 |
| LYM (×109/L) | ||||
| Reduced | 112/222 (50.5) | 40/129 (31.0) | 90/204 (44.1) | 0.002 |
| Hb (g/L) | ||||
| Reduced | 45/222 (20.3) | 24/131 (18.3) | 55/211 (26.1) | 0.182 |
| PLT (×109/L) | ||||
| Reduced | 47/222 (21.2) | 14/129 (10.9) | 54/204 (26.5) | 0.003 |
| CRP (mg/L) | ||||
| Elevated | 80/260 (30.8) | 33/128 (25.8) | 22/103 (21.4) | 0.175 |
| PCT (ng/mL) | ||||
| Elevated | 289/290 (99.7) | 121/123 (98.4) | 187/193 (96.9) | 0.046 |
| ALT (U/L) | ||||
| Elevated | 12/316 (3.8) | 5/145 (3.5) | 29/289 (10.0) | 0.002 |
| AST (U/L) | ||||
| Elevated | 97/322 (30.1) | 34/145 (23.5) | 116/289 (40.1) | 0.001 |
| CK (U/L) | ||||
| Elevated | 52/317 (16.4) | 21/147 (14.3) | 44/287 (15.3) | 0.827 |
| CK-MB (U/L) | ||||
| Elevated | 310/317 (97.7) | 140/147 (95.2) | 271/287 (94.4) | 0.043 |
Note: Data are n (%)
WBC: white blood cell; LYM: lymphocyte; Hb: hemoglobin; PLT: platelet; CRP: C-reactive protein; PCT: procalcitonin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CK: creatine kinase; CK-MB: creatine kinase-MB
Elevated: exceeding the upper limit of the normal range. Reduced: below the lower limit of the normal range