Table 3.
Univariable and multivariable logistic regression analysis of the factors of cognitive impairment at baseline after propensity score matching
| Characteristics | Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|---|
| β | HR(95%CI) | P-Value | β | HR(95%CI) | P-Value | ||
| Age,y | 0.087 | 1.091(1.030–1.155) | 0.003 | ||||
| Menopausal status | No | Reference | Reference | ||||
| Yes | 1.009 | 2.742(1.435–5.239) | 0.002 | 1.155 | 3.174(1.625–6.201) | < 0.001 | |
| Comorbidities | No | Reference | |||||
| Yes | -0.089 | 0.915(0.427–1.962) | 0.915 | ||||
| Education level | Elementary/Junior high | Reference | |||||
| Senior high/College and above | -0.971 | 0.379(0.200–0.719) | 0.003 | ||||
| Marital status | Single, divorced, or Widowed | Reference | |||||
| Married | 0.080 | 1.083(0.407–2.883) | 0.873 | ||||
| Employment status | Unemployed | Reference | |||||
| Employed | -0.885 | 0.413(0.212–0.805) | 0.009 | ||||
| Income status (¥) | < 4000 | Reference | |||||
| ≥ 4000 | -0.371 | 0.690(0.368–1.295) | 0.248 | ||||
| Residence | Rural | Reference | Reference | ||||
| Urban | -1.232 | 0.292(0.130–0.656) | 0.003 | -1.391 | 0.249(0.108–0.572) | 0.001 | |
| Family history of cancer | No | Reference | |||||
| Yes | -0.029 | 0.972(0.391–2.417) | 0.951 | ||||
| FNA | No | Reference | |||||
| Yes | -0.085 | 0.919(0.477–1.769) | 0.800 | ||||
| Thyroidectomy | less than total thyroidectomy | Reference | |||||
| total thyroidectomy | 0.062 | 1.064(0.576–1.969) | 0.843 | ||||
| Lymph node dissection | Central | Reference | |||||
| Lateral | -0.077 | 0.926(0.286–2.999) | 0.898 | ||||
| Surgical approach | Remote-access | Reference | |||||
| Conventional transcervical | 0.437 | 1.548(0.558–4.291) | 0.401 | ||||
| T classification | T1 | Reference | |||||
| T2 | -0.199 | 0.819(0.210–3.203) | 0.774 | ||||
| N classification | N0 | Reference | |||||
| N1a | -0.723 | 0.485(0.252–0.935) | 0.031 | ||||
| N1b | -0.427 | 0.653(0.193–2.202) | 0.492 | ||||
| Stage | I | Reference | |||||
| II | -0.262 | 0.769(0.145–4.082) | 0.758 | ||||
| Risk | low-risk | Reference | |||||
| Middle-risk | -0.566 | 0.568(0.267–1.205) | 0.141 | ||||
| High-risk | -0.316 | 0.729(0.184–2.882) | 0.652 | ||||
| FT3a(pmol/L) | -0.396 | 0.673(0.367–1.236) | 0.202 | ||||
| FT4a(pmol/L) | -0.054 | 0.948(0.779–1.154) | 0.593 | ||||
| TSHa(mIU/L) | 0.002 | 1.002(0.763–1.317) | 0.987 | ||||
Comorbidities includ Hypertension, coronary heart disease, diabetes
Italics indicate statistical significance
Abbreviations: y years, FNA fine needle aspiration biopsy, FT3 free triiodothyronine, FT4 free thyroxine, TSH Thyroid Stimulating Hormone
aThe analysis was carried out in 197 samples