Table 1. Pretreatment characteristics of 88 patients with advanced gastric cancer.
| Variables | Number of patients (%) |
|---|---|
| Age (years) | |
| ≥60 | 45 (51.1) |
| <60 | 43 (48.9) |
| Gender | |
| Male | 48 (54.4) |
| Female | 40 (45.6) |
| Location | |
| Cardia | 9 (10.2) |
| Antrum | 36 (40.9) |
| Gastric body | 43 (48.9) |
| Histological grade | |
| Poor-differentiated | 82 (91.1) |
| Moderately | 8 (9.1) |
| Clinical stage | |
| III | 11 (12.5) |
| IV | 77 (87.5) |
| HER-2 | |
| Negative | 77 (87.5) |
| Positive | 11 (12.5) |
| MSI-high | |
| Negative | 86 (97.7) |
| Positive | 2 (2.3) |
| CPS | |
| <1 score | 85 (96.6) |
| 1 score | 1 (1.1) |
| 10 score | 2 (2.3) |
| ECOG PS | |
| 0 score | 70 (79.5) |
| 1 score | 18 (20.5) |
| Line of therapy | |
| Conversion therapy | 11 (12.5) |
| First-line therapy | 77 (87.5) |
| BMI (kg/m2) | |
| Underweight (<18.5) | 25 (28.4) |
| Normoweight (18.5–24.9) | 52 (59.1) |
| Overweight (≥25) | 11 (12.5) |
| Baseline indicatora | |
| NLR | |
| <2.84 | 45 (51.1) |
| ≥2.84 | 43 (48.9) |
| NER | |
| <86.72 | 62 (75.6) |
| ≥86.72 | 20 (24.4) |
| PLR | |
| <82.23 | 10 (11.4) |
| ≥82.23 | 78 (88.6) |
| LMR | |
| <2.35 | 33 (37.5) |
| ≥2.35 | 55 (62.5) |
| HALP | |
| <31.17 | 50 (56.8) |
| ≥31.17 | 38 (43.2) |
| SII | |
| <814.8 | 55 (62.5) |
| ≥814.8 | 33 (37.5) |
| Albumin (g/L) | |
| <41.65 | 46 (52.3) |
| ≥41.65 | 42 (47.7) |
| Total protein (g/L) | |
| <67.70 | 35 (39.8) |
| ≥67.70 | 53 (60.2) |
| PNI | |
| <46.53 | 33 (37.5) |
| ≥46.53 | 55 (62.5) |
Notes:
a
Baseline indicators are classified into two categories by the cut-off values calculated by Receiver Operating Characteristic Curve.
Abbreviation used: MSI, Microsatellite Instability; CPS, Combined Positive Score; ECOG PS, Eastern Cooperative Oncology Group Performance Status; BMI, Body Mass Index; NLR, neutrophil count to lymphocyte count ratio; NER, neutrophil count to eosinophil count ratio; PLR, platelet count to lymphocyte count ratio; LMR, lymphocyte count to monocyte count ratio; HALP, the hemoglobin, albumin, lymphocyte and platelet score; PNI, prognostic nutritional index; SII, systemic immune-inflammation index.