Table 4. Correlation between baseline nutritional indicators and clinical response (ORR, DCR) in 88 patients with advanced gastric cancer.
| Responses group | Non-ORR N (%) | ORR N (%) | χ2 (ORR) | P value (ORR) | Non-DCR N (%) | DCR N (%) | χ2 (DCR) | P value (DCR) |
|---|---|---|---|---|---|---|---|---|
| BMI (kg/m2) | 4.463 | 0.107 | 5.813 | 0.055 | ||||
| Underweight (<18.5) | 8 (32.0) | 17 (68.0) | 7 (28.0) | 18 (72.0) | ||||
| Normoweight (18.5–24.9) | 12 (23.1) | 40 (76.9) | 6 (11.5) | 46 (88.5) | ||||
| Overweight (≥25) | 0 (0.0) | 11 (100.0) | 0 (0.0) | 11 (100.0) | ||||
| Albumin (g/L) | 5.359 | 0.021 | 0.525 | 0.469 | ||||
| <41.65 | 15 (32.6) | 31 (67.4) | 8 (17.4) | 38 (82.6) | ||||
| ≥41.65 | 5 (11.9) | 37 (88.1) | 5 (11.9) | 37 (88.1) | ||||
| Total protein (g/L) | 0.295 | 0.587 | 1.261 | 0.261 | ||||
| <67.70 | 9 (25.7) | 26 (74.3) | 7 (20.0) | 28 (80.0) | ||||
| ≥67.70 | 11 (20.8) | 42 (79.2) | 6 (11.3) | 47 (88.7) | ||||
| PNI | 8.351 | 0.004 | 1.739 | 0.187 | ||||
| <46.53 | 13 (39.4) | 20 (60.6) | 7 (21.2) | 26 (78.8) | ||||
| ≥46.53 | 7 (12.7) | 48 (87.3) | 6 (10.9) | 49 (89.1) |
Note:
Abbreviation used: ORR, objective response rate; DCR, disease control rate; N, number of patients; BMI, Body Mass Index; PNI, prognostic nutritional index.