Table 4.
Multivariate Cox analysis of DFS and OS
| DFS | OS | |||
|---|---|---|---|---|
| Items | HR (95%CI) | P | HR (95%CI) | P |
| Age | 1.002(0.994–1.010) | 0.563 | 1.004(0.996–1.012) | 0.338 |
| BMI | 1.005(0.975–1.014) | 0.589 | 1.006(0.974–1.014) | 0.554 |
| ANLR | ||||
| < 1.05 | Ref | Ref | ||
| ≥ 1.05 | 3.551(2.547–4.982) | < 0.001 | 3.798(2.987–4.679) | < 0.001 |
| Tumor size | ||||
| < 30 mm | Ref | Ref | ||
| 30–50 mm | 1.057(0.898–1.255) | 0.523 | 1.185(0.787–1.332) | 0.222 |
| > 50 mm | 1.139(0.850–1.525) | 0.383 | 1.360(0.997–1.959) | 0.063 |
| LNP | ||||
| Negative | Ref | Ref | ||
| Positive | 1.544(1.238–2.421) | < 0.001 | 1.995(1.595–2.496) | < 0.001 |
| Histological Grading | ||||
| Grade I | Ref | Ref | ||
| Grade II | 1.389(0.926–2.083) | 0.147 | 1.120(0.835–1.501) | 0.450 |
| Grade III | 1.164(0.783–1.852) | 0.253 | 1.055(0.878–1.517) | 0.737 |
| TNM stage | ||||
| II | Ref | Ref | ||
| III | 2.582(1.771–4.674) | < 0.001 | 2.796(1.555–4.021) | < 0.001 |
DFS: Disease-Free Survival; OS: Overall survival; HR: Hazard ratio; BMI: Body mass index; ANLR: Alb and Neutrophil-Lymphocyte Ratio; LNP: lymph node positivity