Fig. 3.

Gene expression levels of Piezo1 (A), Cav1 (C), Nlrp3 (E), Nlrp6 (G), Il1b (I) and Col11a1 (K) in the epididymal adipose tissue (EWAT) from rats fed a normal diet (ND) or a high-fat diet (HFD) and (B, D, F, H, J, L) after being submitted to sham surgery, single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S), sleeve gastrectomy (SG) and pair-fed (PF). Differences between groups were analyzed by unpaired two-tailed Student’s t test as well as by one-way ANOVA followed by Tukey’s tests. ^*P < 0.05, ^**P < 0.01 and ^***P < 0.001. Cav1, caveolin 1; Col1a1, collagen 1a1; Il1b, interleukin-1β; Nlrp, nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin