Fig. 4.

(a) Phylogenetic tree of DGR reverse transcriptases (amino acid sequences). The inner ring represents the environment (biome), middle rings show the taxonomic annotation at domain and phylum level, and the outer ring represents the cassette architecture. The branches are colored according to their environments(biomes). We identified 9 main clades that are delimited by the dashed lines. (b) Representation of the 6 most common DGR cassette architectures