Fig. 2.

Baicalin regulated the ileal microbiota composition disrupted by E. coli infection (n = 8). A PCoA analysis of microbiota in ileum based on weighted UniFrac distance metrics. B Alpha-diversity (Sobs and Chao index) of microbiota. Intergroup difference test was performed by Wilcoxon rank-sum test. * means P < 0.05. C–E Relative abundance of microbiota at phylum level (C), genus levels (D), and species level (E). Less than 1% abundance of phyla or genus was merged into others. F Proportions of key genus and species in three groups. Intergroup difference test was performed by Wilcoxon rank-sum test. * means P < 0.05. G LEfSe analysis of microbiota. H LEfSe Bar