Skip to main content
. 2024 Dec 20;19(12):e0305440. doi: 10.1371/journal.pone.0305440

Table 2. Gene expression of candidate transcription factors in bovine mammary epithelial cells across all timepoints of 24, 40, 48 and 60 h after lysine or methionine subtraction to ¼ the normal concentration1.

Gene Treatment2 SEM P-value3
CTL LK LM LK LM
ATF4 1.17 1.42 1.47 0.40 0.04 0.01
ATF6 1.15 1.18 1.36 0.13 0.78 0.01
FOS 3.41 3.56 3.24 1.30 0.71 0.65
JUN 3.37 2.39 2.22 1.10 0.17 0.09
EGR1 2.20 2.13 1.72 0.71 0.81 0.05
MYC 2.46 2.37 2.58 0.85 0.69 0.54
HIF1A 1.43 1.37 1.65 0.20 0.42 <0.01
SREBF1 0.91 0.84 0.88 0.06 0.04 0.33

1Values are least squares means ± SE (n = 12) in arbitrary units.

2CTL = control; LK = low lysine; LM = low methionine.

3Linear contrast of LK or LM vs. CTL.