Table 2. Gene expression of candidate transcription factors in bovine mammary epithelial cells across all timepoints of 24, 40, 48 and 60 h after lysine or methionine subtraction to ¼ the normal concentration1.
Gene | Treatment2 | SEM | P-value3 | |||
---|---|---|---|---|---|---|
CTL | LK | LM | LK | LM | ||
ATF4 | 1.17 | 1.42 | 1.47 | 0.40 | 0.04 | 0.01 |
ATF6 | 1.15 | 1.18 | 1.36 | 0.13 | 0.78 | 0.01 |
FOS | 3.41 | 3.56 | 3.24 | 1.30 | 0.71 | 0.65 |
JUN | 3.37 | 2.39 | 2.22 | 1.10 | 0.17 | 0.09 |
EGR1 | 2.20 | 2.13 | 1.72 | 0.71 | 0.81 | 0.05 |
MYC | 2.46 | 2.37 | 2.58 | 0.85 | 0.69 | 0.54 |
HIF1A | 1.43 | 1.37 | 1.65 | 0.20 | 0.42 | <0.01 |
SREBF1 | 0.91 | 0.84 | 0.88 | 0.06 | 0.04 | 0.33 |
1Values are least squares means ± SE (n = 12) in arbitrary units.
2CTL = control; LK = low lysine; LM = low methionine.
3Linear contrast of LK or LM vs. CTL.