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. 2024 Dec 20;19(12):e0305440. doi: 10.1371/journal.pone.0305440

Table 3. Cell activities in bovine mammary epithelial cells across both timepoints of 48 and 60 h after lysine or methionine subtraction to ¼ the normal concentration1.

Item Treatment2 SEM P-value3
CTL LK LM LK LM
Protein synthesis rate 272 213 186 11.5 <0.01 <0.01
Fat synthesis rate 83.4 81.5 76.1 8.0 0.87 0.53
Cell proliferation rate 13.2 10.5 8.4 0.8 0.03 <0.01
PDI (arbitrary units) 0.66 0.70 0.50 0.03 0.93 0.72

1Values are least squares means ± SE (n = 6) in dpm/ng DNA unless otherwise stated.

2CTL = control; LK = low lysine; LM = low methionine; PDI = endoplasmic reticulum tracker protein disulfide isomerase.

3Linear contrast of LK or LM vs. CTL.