Table 2.
Comparative Analysis of Clinical-Radiological Features Between non-IMA and IMA Within the Training Dataset.
| Variables | Total (n = 922) | Non-IMA (n = 841) | IMA (n = 81) | P-value |
|---|---|---|---|---|
| Sex, n (%) | .458 | |||
| Female | 587 (63.7) | 539 (64.1) | 48 (59.3) | |
| Male | 335 (36.3) | 302 (35.9) | 33 (40.7) | |
| Age, Median (Q1, Q3) | 57 (51, 66) | 57 (51, 66) | 60 (53, 67) | .121 |
| Laterality, n (%) | .57 | |||
| Left | 388 (42.1) | 351 (41.7) | 37 (45.7) | |
| Right | 534 (57.9) | 490 (58.3) | 44 (54.3) | |
| Primary site, n (%) | < .001 | |||
| Lower lobe | 303 (32.9) | 253 (30.1) | 50 (61.7) | |
| Middle lobe | 67 (7.3) | 60 (7.1) | 7 (8.6) | |
| Upper lobe | 552 (59.9) | 528 (62.8) | 24 (29.6) | |
| Clinical T stage, n (%) | < .001 | |||
| cT1a | 64 (6.9) | 64 (7.6) | 0 (0) | |
| cT1b | 480 (52.1) | 448 (53.3) | 32 (39.5) | |
| cT1c | 378 (41) | 329 (39.1) | 49 (60.5) | |
| CT density, n (%) | < .001 | |||
| GGN | 390 (42.3) | 386 (45.9) | 4 (4.9) | |
| SN | 305 (33.1) | 250 (29.7) | 55 (67.9) | |
| SSN | 227 (24.6) | 205 (24.4) | 22 (27.2) | |
| Margin, n (%) | .744 | |||
| Ill-defined | 201 (21.8) | 185 (22) | 16 (19.8) | |
| Well-defined | 721 (78.2) | 656 (78) | 65 (80.2) | |
| Shape, n (%) | .005 | |||
| Irregular | 414 (44.9) | 365 (43.4) | 49 (60.5) | |
| Round/oval | 508 (55.1) | 476 (56.6) | 32 (39.5) | |
| Lobulation, n (%) | .018 | |||
| Absence | 382 (41.4) | 359 (42.7) | 23 (28.4) | |
| Presence | 540 (58.6) | 482 (57.3) | 58 (71.6) | |
| Spiculation, n (%) | .087 | |||
| Absence | 465 (50.4) | 432 (51.4) | 33 (40.7) | |
| Presence | 457 (49.6) | 409 (48.6) | 48 (59.3) | |
| Vascular change, n (%) | .383 | |||
| Absence | 209 (22.7) | 187 (22.2) | 22 (27.2) | |
| Presence | 713 (77.3) | 654 (77.8) | 59 (72.8) | |
| Bubble lucency, n (%) | < .001 | |||
| Absence | 757 (82.1) | 707 (84.1) | 50 (61.7) | |
| Presence | 165 (17.9) | 134 (15.9) | 31 (38.3) | |
| Pleural indentation, n (%) | .404 | |||
| Absence | 399 (43.3) | 368 (43.8) | 31 (38.3) | |
| Presence | 523 (56.7) | 473 (56.2) | 50 (61.7) | |
Abbreviation: GGN, ground-glass nodule; SN, solid nodule; SSN, subsolid nodule; IMA, invasive mucinous adenocarcinoma.