Table 2.
Maternal nutrient supplement and serum biomarkers of the study subjects
| Control (N = 77) n (%) or median (interquartile) |
Case (N = 53) n (%) or median (interquartile) |
P value | |
|---|---|---|---|
| Nutrient supplement | |||
| FA supplementation | 0.939a | ||
| Irregularly | 30(39.0) | 21(39.6) | |
| Regularly | 47(61.0) | 32(60.4) | |
| Multivitamin supplementation | 0.039a | ||
| Irregularly | 43(55.8) | 39(73.6) | |
| Regularly | 34(44.2) | 14(26.4) | |
| Nutrient serum biomarkers | |||
| Folate (nmol/L) | 29.3(13.3) | 33.9(15.8) | 0.113b |
| Vitamin B12 (pmol/L) | 284.0(139.5) | 253.0(108.5) | 0.029b |
| Homocysteine (µmol/L) | 4.5(3.0) | 6.44(3.3) | <0.001b |
a: P value was calculated by chi-squared test; b: P value was calculated by Mann–Whitney U-test