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. 2024 Dec 20;15:494. doi: 10.1186/s13287-024-04114-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 2 — Glial expression in the hippocampus of CRS mice after NIR treatment. (A) Representative image of immunohistochemical staining for PCNA in the non-stimulated and stimulated DG regions of CRS mice. (B) Relative intensity value of fluorescence after homogenization (CRS: n = 3; CRS + NIR: n = 3; two slices per mice). (C) Representative images of immunofluorescence staining of GFAP in the non-stimulated and stimulated DG regions of CRS mice. (D) Relative intensity value of fluorescence after homogenization (CRS: n = 3; CRS + NIR: n = 3; two slices per mice). (E) Representative image of immunohistochemical staining for S100 in the non-stimulated and stimulated DG regions of CRS mice. (F) Relative intensity value of fluorescence after homogenization (CRS: n = 3; CRS + NIR: n = 3; two slices per mice).Values represent mean ± SEM, ***p < 0.001. (G) Representative image of immunohistochemical staining for MAP2 in the non-stimulated and stimulated SGZ regions of CRS mice. (H) Relative intensity value of fluorescence after homogenization (CRS: n = 3; CRS + NIR: n = 3; two slices per mice).Values represent mean ± SEM, ***p < 0.001