Table 2.

The association between pulmonary ventilation function and mild cognitive impairment

Pulmonary Function	No. of controls/cases (n = 2099/238)	OR (95%CI)	P
Pulmonary ventilation function1
NPF	1256/119	1.00
PPF	843/119	1.38 (1.04, 1.83)	0.026
Pulmonary ventilation function2
Normal	1256/119	1.00
Mild impairment	774/103	1.33 (0.99, 1.79)	0.061
Moderate to severe impairment	69/16	2.10 (1.07, 3.96)	0.026
Obstructive pulmonary ventilation dysfunction3
No	1270/122	1.00
Yes	829/116	1.35 (1.01, 1.79)	0.040
COPD4
No	1823/182	1.00
Yes	276/56	1.60 (1.09, 2.32)	0.014
Restrictive pulmonary ventilation dysfunction5
No	2049/228	1.00
Yes	50/10	1.76 (0.80, 3.54)	0.135
Small airways dysfunction6
No	394/37	1.00
Yes	1705/201	1.05 (0.72, 1.56)	0.819

Model 1: adjusted for gender, education level, BMI, and history of respiratory disease and dyslipidemia. Model 2: adjusted for gender, age, education level, BMI, smoking, anxiety, and history of respiratory disease and dyslipidemia. Model 3: adjusted for gender, education level, BMI and history of respiratory disease and dyslipidemia. Model 4: adjusted for gender, age, education level, smoking, drinking, and history of hypertension, diabetes, respiratory disease and dyslipidemia. Model 5: adjusted for gender, age, smoking, and history of respiratory disease and hypertension. Model 6: adjusted for gender, education level, and history of respiratory disease and dyslipidemia. NPF, normal pulmonary function; PPF, poor pulmonary function