Figure 6.

Hsa_circ_100791 exerts biological functions in AR by regulating the expression of miR-487b-5p. (A) qRT-PCR analysis of the expression protein level of TRIM13 in HNEpCs co-transfected with vector+ mimics NC or oe- circ-100791 + mimics NC or oe- circ-100791 + miR-487b-5p mimics. (B) Western blot analysis of the expression protein level of Trim13 in HNEpCs co-transfected with vector+ mimics NC or oe- circ-100791 + mimics NC or oe- circ-100791 + miR-487b-5p mimics. (C–G) qRT-PCR analysis of the expression protein level of IL-4, IL-5, IL-33, TNF-α and IFN-γ in HNEpCs co-transfected with vector+ mimics NC or oe- circ-100791 + mimics NC or oe- circ-100791 + miR-487b-5p mimics. Data were presented as mean ± SEM. N=3 for each group.

Abbreviations: AR, allergic rhinitis; NC, negative control; oe- circ-100791, overexpression circ-100791; SEM, standard error of mean.