Table 1.
Characteristics of 45 Patients with P. Jirovecii Infection and Colonization
| Groups | Age | Gender Number (%) | GR% | LY% | HGB | PLT | TP | ALB | CRP | PCT | LDH | Quantification of P. jirovecii/Copies | Treatment | Prognosis | Diagnostic Criteria | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Inpatient Days |
Death toll |
|||||||||||||||
| P. jirovecii infection (n=14, all immunosuppressed) | 59.5 (45.8, 68) | Female:1(7.1%) Male:13(92.9%) |
81.8±12.7 | 9.2 (5.7, 18.5) | 86 (73.5, 112.3) | 189 (80.3, 263.5) | 52.7±6.8 | 27.8±5.2 | 49.7 (21.3, 74.5) | 0.3 (0.2, 3.6) | 464 (148.3, 560.8) | 5.6×105 (2.5×104, 1.5×106) | TMP-SMX | 22 (15.8, 24.5) | 2 | ① clinical manifestation, ② imaging characteristics ③ conventional PCR which amplifies P. jirovecii mtLSU gene from sputum/BALF specimens. |
| P. jirovecii colonization (n=31, including 7 immunosuppressed) | 67 (15, 81) | Female:9 (29.0%) Male:22 (71.0%) |
72.1±13.9 | 16.3 (8.8, 27.8) | 122 (84.5, 146) | 220 (137, 270) | 59.4±8.3 | 31.7±5.1 | 3.5(0.6, 25.2) | 0.6 (0.4, 1.6) | 231.5 (193.8, 275.3) | 5.1×104 (1.6×104, 1.6×105) | Not treated according to PJP and treated according the underlying diseases. | 12 (9, 22.5) | 2 | These patients with clinical manifestation and P. jirovecii DNA positive using qPCR methods (Wu et al, 2021), while, the imaging characteristics did not support the diagnosis of PJP. |
| P value | 0.606 | 0.102 | 0.034 | 0.031 | 0.024 | 0.351 | 0.011 | 0.023 | 0.004 | 0.192 | 0.481 | 0.005 | – | 0.005 | 0.578 | – |
Notes: –: no data; Continuous variables were presented as P50 (P25, P75) or average (±SD). We compared between P. jirovecii infection and colonization groups and Bold indicates statistical significance (P<0.05).
Abbreviations: GR%, granulocyte percentage; LY%, lymphocyte percentage; HGB, hemoglobin; PLT, platelet; TP, total protein; ALB, albumin; CRP, C-reactive protein; PCT, procalcitonin; LDH, lactate dehydrogenase.