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. 2024 Dec 17;19:13507–13524. doi: 10.2147/IJN.S488357

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© 2024 Li et al.

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The therapeutic efficacy of Cu_4.5O USNPs in sepsis was assessed through histopathological analysis. (A–D) H&E staining of important organ tissues. All scale bars of H&E staining images are 50 μm, n=3. (E–H) Quantitative pathology scores in different organs, n=6. (I–L) Levels of organ function indicators in blood, n=6. “*” = P < 0.05, “**” = 0.001 < P < 0.01, “***” = 0.0001 < P < 0.001, “****” = P < 0.0001.

Abbreviations: LPS, Lipopolysaccharide; ALT, Alanine transaminase; AST, Aspartate aminotransferase; CRE, Creatinine; BUN, Blood Urea Nitrogen; ns, no significant difference between groups.