Fig. 8.

OPC formation and myelination in SCI rats. a–d Immunofluorescence assay indicated that TET3-OE can express the OPC-specific markers NG2 (a, c) and PDGFRA (b, d) in vivo at 14 days post injury. e, f MBP immunofluorescence staining reveals significantly higher MBP expression in the TET3-OE group. Data are shown as mean ± standard deviation. n = 6 rats, scale bar = 500 μm. Statistical analysis was performed using one-way ANOVA with Tukey’s HSD post-hoc test. *p < 0.05, ***p < 0.001 vs SCI group, ^##p < 0.01, ^###p < 0.001 vs sham group, ■■p < 0.01, ■■■p < 0.001 vs TET3-OE group