Table 1.

Nanoparticles in Bladder Cancer Therapy

Therapies	Nanocarriers	Payloads	Anti-tumor Strategy	References
Chemotherapy	Nanodiamond	VitaminA analogs	Enhanced the penetration into tumor	[7,8]
		Doxorubicin	Enhanced cytotoxicity
	Polymeric nanostructure	Pirabucin	Efficient delivery	[9]
	Nanoliposome	Vincristine	Reduced side effects	[10,11]
	Poly(L-aspartic acid sodium salt) nanoparticle	Cisplatin	Reduced side effects	[12]
	Glutathione-responsive nanoparticle	Cisplatin prodrug (Pt(IV))	Overcome drug resistance	[13]
Gene Therapy	Mesoporous silica nanoparticles	siRNA	Enhanced targeting ability	[14]
	Lipid nanoparticle			[15]
	Chrysotile nanotubes	circRNA	Enhanced passive targeting ability	[16]
	Exosome		Enhanced active targeting ability	[17,18]
Immunotherapy	MNC-ICG-NIG@SiO2 nanoparticles	BCG	Precisely controlled of drug release in tumor	[19]
	Macrophage-derived exosome-mimetic nanovesicles	PD-L1 inhibitor	Blocking immunosuppression	[20]
	Poly (propylglycolide-co-glycolide) nanoparticles	Toll-like receptor 7/8 agonist	Enhanced immune response	[21]
Phototherapy	HSA-Ce6/NTZ/FCS nanoparticles	Chlorin e6	Enhanced transmucosal delivery	[22]
	Tumor-specific ligands	Chlorin e6	Enhanced targeting ability	[23]
	Mesoporous silica nanoparticles	-	Enhanced phototoxicity	[24]
	Gold nanorods	MnO2	Enhanced drug release in tumor microenvironment	[25]