Table 1. Sample size estimation using the intraclass correlation coefficient based on Giraudeau and Mary.
Number of participants required for a 95% CI at three confidence levels | ||||
---|---|---|---|---|
Number of observers | Expected ICC | ± 0.05 | ± 0.10 | ± 0.15 |
2 | 0.9 | 56 | 14 | 4 |
0.8 | 200 | 50 | 13 | |
0.7 | 400 | 100 | 25 | |
0.6 | 630 | 158 | 40 | |
0.5 | 865 | 217 | 55 | |
4 | 0.9 | 36 | 9 | 3 |
0.8 | 119 | 30 | 8 | |
0.7 | 222 | 56 | 14 | |
0.6 | 322 | 81 | 21 | |
0.5 | 401 | 101 | 26 | |
6 | 0.9 | 31 | 8 | 2 |
0.8 | 103 | 26 | 7 | |
0.7 | 187 | 47 | 12 | |
0.6 | 263 | 66 | 17 | |
0.5 | 314 | 79 | 20 | |
10+ | 0.9 | 29 | 8 | 2 |
0.8 | 92 | 23 | 6 | |
0.7 | 164 | 41 | 11 | |
0.6 | 224 | 56 | 14 | |
0.5 | 259 | 65 | 17 |
Abbreviations: CI, confidence interval; ICC, intraclass correlation coefficient.
Note: Adapted from Karanicolas et al. 14