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. 2024 Nov 21;16(11):e74182. doi: 10.7759/cureus.74182

Table 3. Percentage of patients with elevated levels of LDH, CRP, and D-Di in different immune statuses and different vaccination scenarios.

* Using the chi-square test, P < 0.05 indicates statistical significance.

P1: significance of the unvaccinated group compared to the vaccinated group; P2: significance of the ≧1 group compared to the <1 group, P3: significance of comparison of groups A and C; P4: significance of comparison of groups B and D.

≧1: patient's lymphocyte count on admission ≧1 (10^9/L); <1: patient's lymphocyte count on admission <1 (10^9/L).

LDH: lactate dehydrogenase; CRP: C-reactive protein; D-Di: D-dimer.

Laboratory test Total (n = 338) Unvaccinated (n = 117) Vaccinated (n = 221) ≧1 (n = 159) <1 (n = 179) Group P1 P2 P3 P4
Unvaccinated Vaccinated
≧1 <1 ≧1 <1
A (n =51) B (n = 66) C (n = 108) D (n = 113)
LDH (U/L), n (%)                   0.171 0.028 0.144 0.709
0-225 153 (45.30) 47 (40.2) 106 (48.0) 82 (51.6) 71 (39.7) 22 (43.10) 25 (37.90) 60 (55.60) 46 (40.70)        
>225 185 (54.70) 70 (59.8) 115 (52.0) 77 (48.4) 108 (60.3) 29 (56.90) 41 (62.10) 48 (44.40) 67 (59.30)        
CRP (mg/L), n (%)                   0.025 0.048 0.262 0.055
0-10 128 (38.32) 35 (29.9) 93 (42.1) 69 (43.4) 59 (33.0) 19 (37.25) 16 (24.20) 50 (46.30) 43 (38.10)        
>10 210 (62.10) 82 (70.1) 128 (57.9) 90 (56.6) 120 (67.0) 32 (62.75) 50 (75.80) 58 (53.70) 70 (61.90)        
D-Di (mg/L), n (%)                   0.003 0.002 0.091 0.012
0-550 107 (31.70) 23 (19.7) 84 (38.0) 66 (41.5) 41 (22.9) 15 (29.41) 8 (12.10) 51 (47.20) 33 (29.20)        
>550 231 (68.30) 94 (80.3) 137 (62.0) 93 (58.5) 138 (77.1) 36 (70.59) 58 (87.90) 57 (52.80) 80 (70.80)