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Que mitigated DSS-induced ulcerative colitis. (A) Perianal conditions of mice in each group. (B) Body weight changes in mice (n = 10). (C) Variations in the disease activity index (DAI) in mice (n = 10). (D–E) Colon length measurements in mice (n = 10). (F–G) mRNA expression levels of TNF-α and IL-1β in the colon as determined by qPCR (n = 3). (H, I) Serum levels of TNF-α and IL-1β (n = 6). (J) Experimental design. (K) Chemical structure of Que. *p < 0.05, **p < 0.01, ***p < 0.001.
