Skip to main content
. 2024 Dec 9;15:1466208. doi: 10.3389/fphar.2024.1466208

FIGURE 9.

FIGURE 9

Z-LIG/CGA regulates IL-1R2/IL-17RA/STAT1 signaling pathway to inhibit cardiomyocyte apoptosis in mice. (A) Representative western blots and quantification of Bcl-2, BAX expression in the hearts from each group. (B) Representative western blots and quantification of Cleaved Caspase-3, Caspase-3 expression in the hearts from each group. (C) Representative western blots and quantification of IL-1R2 expression in the hearts from each group. (D) Representative western blots and quantification of IL-17RA expression in the hearts from each group. (E) Representative western blots and quantification of p-JAK1, T-JAK1 expression in the hearts from each group. (F) Representative western blots and quantification of p-STAT1, T-STAT1 expression in the hearts from each group. Data are expressed as mean ± SD (n = 4). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. Control group. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Model group. +P < 0.05, ++P < 0.01, +++P < 0.001 vs. ZC group.