Table 2.
Transthoracic echocardiographic variables before and after at discharge transcatheter edge-to-edge mitral valve repair (n = 46).
| Baseline | Post-procedure* | p value | |
|---|---|---|---|
| Left atrial to aortic dimension ratio (short axis) (LA/Ao) | 2.4 (2.0, 2.7) | 2.2 (1.8, 2.6) | <0.001 |
| Left atrial to aortic dimension ratio (long axis) (LA/Ao) | 3.8 (3.4, 4.2) | 3.5 (3.0, 4.0) | <0.001 |
| LA volume end-systole (mL/kg) | 4.8 (4.0, 5.6) | 3.7 (2.7, 4.6) | <0.001 |
| Left ventricular internal dimension in diastole (LVIDdN cm/kg0.294) | 2.1 (2.0, 2.3) | 2.0 (1.8, 2.1) | <0.001 |
| LV end-diastolic volume (mL/kg) | 4.6 (4.0, 5.5) | 3.7 (2.8, 4.4) | <0.001 |
| LV end-systolic volume (mL/kg) | 1.0 (0.8, 1.5) | 1.3 (0.9, 1.6) | 0.004 |
| Total stroke volume (mL/kg) | 3.6 (3.2, 4.0) | 2.2 (1.7, 3.0) | <0.001 |
| Forward stroke volume (mL/kg) | 1.3 (1.0, 1.5) | 1.2 (1.0, 1.6) | 0.35 |
| Regurgitant volume (mL/kg) | 2.3 (1.9, 3.1) | 1.1 (0.3, 1.8) | <0.001 |
| Regurgitant fraction (%) | 65 (58, 76) | 43 (14, 61) | <0.001 |
| EROA (cm2/m2) | 0.60 (0.40, 0.80) | 0.25 (0.10, 0.50) | <0.001 |
| Mitral inflow E-wave velocity (m/s) | 1.2 (1.1, 1.4) | 0.9 (0.8, 1.1) | <0.001 |
| Mean mitral inflow pressure gradient (mmHg) | 1.5 (1.0, 2.0) | 1.5 (1.0, 2.3) | 0.73 |
| Heart rate (bpm) | 120 (100, 132) | 110 (90, 130) | 0.07 |
| Tricuspid regurgitation peak velocity (m/s) | 2.7 (2.4, 3.2) | 2.7 (2.4, 3.1) | 0.08 |
| Ejection fraction (%) | 77.7 (71.6, 80.7) | 63.5 (59.1, 69.6) | <0.001 |
Values reported as median (25th-centile, 75th-centile).
*Obtained 2 to 3 days post-procedure. EROA, effective regurgitant orifice area.