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. 2024 Dec 9;16:1455596. doi: 10.3389/fnagi.2024.1455596

TABLE 1.

Characteristics and group differences between patients with (CI group) and without cognitive impairment (NCI group).

Variables NCI group (n = 75) CI group (n = 45) P
Age (year) 51.87 ± 13.18 65.02 ± 8.99 < 0.001*
Gender Male 50 (66.67%) 23 (51.11%) 0.092#
Female 25 (33.33%) 22 (48.89%)
Education level < 6 years 3 (4%) 17 (37.78%) < 0.001#
6–12 years 36 (48%) 26 (57.78%)
> 12 years 36 (48%) 2 (4.44%)
Stroke Yes 21 (28%) 20 (44.44%) 0.067#
No 54 (72%) 25 (55.56%)
Take roxadustat N (%) Yes 22 (29.33%) 5 (11.11%) 0.021#
No 53 (70.67%) 40 (88.89%)
Hemodiafiltration Twice/month 23 (30.67%) 15 (33.33%) < 0.001#
Once/month 24 (32%) 15 (33.33%)
No 28 (37.33%) 15 (33.33%)
Hemoperfusion Twice/month 15 (20%) 2 (4.44%) 0.016#
Once/month 9 (12%) 4 (8.89%)
No 51 (68%) 39 (86.67%)
Hemoglobin (g⋅L–1) 108.8 ± 19.57 112.62 ± 17.1 0.28
Total protein (g⋅L–1) 74.87 ± 5.85 69.45 ± 5.89 < 0.001*
Albumin (g⋅L–1) 41.37 ± 2.93 38.45 ± 4.15 < 0.001*
Total bilirubin (μmol⋅L–1) 11.89 ± 4.21 10.38 ± 2.71 0.034*
Serum creatinine (μmol⋅L–1) 939.05 ± 285.08 755.94 ± 197.59 < 0.001*
Serum phosphorus (mmol⋅L–1) 2.12 ± 0.65 1.87 ± 0.58 0.037*
HIF-1α (pg⋅ml–1) 1,272.26 ± 213.66 1,532.76 ± 211.44 < 0.001*
Dialysis duration (month) 19 (11, 62) 30 (13, 60) 0.024&
Intact parathyroid hormone 239.8 (147.9, 365.6) 261 (179.85, 365.25) 0.653&
Serum iron (mmol⋅L–1) 11.1 (9.23, 15.65) 10.40 (7.6, 15.6) 0.494&
Serum ferritin (mmol⋅L–1) 293.55 (171.23, 429.7) 324.9 (168.1, 511.15) 0.653&

*t-test was used for comparing the means.

#Chi-square test was used to compare categorical variables.

&Non-parametric rank sum test to compare medians between two independent samples.