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. 2024 Oct 9;7(1):101229. doi: 10.1016/j.jhepr.2024.101229

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© 2024 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 3 — Multivariate Cox proportional-hazards model investigating associations of different VL trajectory patterns with liver disease progression to fibrosis and/or cirrhosis among adults with chronic HBV infection on NA therapy.

Forest plot showing the hazard ratios and 95% CIs for the development of liver fibrosis and cirrhosis, which were calculated with Cox proportional-hazards model. ADV, adefovir; ALP, alkaline phosphatase; ALT, alanine transaminase; Anti-HBe, Anti-Hepatitis B e-antigen; AST, aspartate aminotransferase; eGFR, estimated glomerular filtration rate; ETV, entecavir; HBV, hepatitis B virus; HBeAg, Hepatitis B e-Antigen; HR, hazard ratio; IMD, Index of Multiple Deprivation; LAM, lamivudine; NA, nucleos(t)ide analogue; TDF, tenofovir disoproxil fumarate; VL, viral load.