Karraz 2003.
Methods | Randomised trial. | |
Participants | 221 women, Evry, France
Inclusion Criteria: Parity: mixed, Pluralty: singleton, Gestation: between 36 and 42 weeks, Onset of labour: spontaneous or scheduled for induced labour, Other: uncomplicated pregnancies. Exclusion criteria ‐ women with pre‐eclampsia or previous caesarean. |
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Interventions |
Study group:
Women could walk, sit in a chair or reclined in a semi‐supine position (n = 141), as long as they demonstrated: acceptable analgesia; acceptable systolic blood pressure and ability to stand on one leg. 3 women in this group were excluded because they had a fast birth. Control group:
Women were not allowed to sit, walk or go to the toilet, they had to remain in the supine position or to lie in a semi‐supine or lateral position (n = 74). 2 women in this group were excluded because they had a fast birth, and another 1 woman was excluded because of inadvertent dural puncture. All women: ‐ Study conducted in daytime only (as women in labour at night are less inclined to walk). ‐ Received intermittent epidural injection of 0.1% ropivacaine with 0.6 µg/mL sufentanil. ‐ Repeat injections were given when the women requested additional pain relief. |
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Outcomes |
Maternal Outcomes:
Neonatal Outcomes: Nil |
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Notes | Duration was recorded as the time between epidural insertion (highly variable) and birth (end of second stage). It was therefore not used as a comparable duration of first stage of labour. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | 'Randomly divided' in a 2:1 ratio. |
Allocation concealment (selection bias) | Unclear risk | Not stated. |
Blinding (performance bias and detection bias) Women | High risk | Not feasible. |
Blinding (performance bias and detection bias) Clinical staff | High risk | Not feasible. |
Blinding (performance bias and detection bias) Outcome assessor | Unclear risk | Not stated. |
Incomplete outcome data (attrition bias) All outcomes | High risk | 6 women were excluded after randomisation. |
Selective reporting (reporting bias) | Unclear risk | Unclear. |