Table 2.
Various acute phase proteins levels in plasma of the study population according to the presence or absence of intra-amniotic inflammation (IAI) and/or microbial invasion of the amniotic cavity (MIAC), acute histologic chorioamnionitis (HCA), and funisitis in women with preterm premature rupture of membranes.
| IAI and/or MIAC | P-value | Acute HCA | P-value | Funisitis | P-value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Positive (n = 93) | Negative (n = 102) | Positive (n = 88) | Negative (n = 84) | Positive (n = 42) | Negative (n = 130) | ||||
| Plasma hepcidin (ng/mL) | 8.38 ± 14.54 | 4.15 ± 5.51 | 0.087 | 7.22 ± 13.29 | 5.20 ± 8.87 | 0.299 | 7.78 ± 17.01 | 5.72 ± 8.79 | 0.774 |
| Plasma MBL (µg/mL) | 1.05 ± 0.57 | 1.05 ± 0.61 | 0.893 | 1.09 ± 0.61 | 1.03 ± 0.61 | 0.510 | 1.04 ± 0.64 | 1.07 ± 0.60 | 0.698 |
| Plasma pentraxin-2 (µg/mL) | 79.26 ± 20.74 | 76.62 ± 18.95 | 0.197 | 76.42 ± 19.22 | 78.90 ± 20.77 | 0.239 | 73.14 ± 22.47 | 79.09 ± 18.96 | 0.113 |
| Plasma RBP4 (µg/mL) | 15.78 ± 4.99 | 17.97 ± 4.25 | <0.001 | 16.14 ± 4.83 | 17.72 ± 4.69 | 0.071 | 14.81 ± 4.22 | 17.60 ± 4.82 | 0.006 |
| Plasma SAA1 (µg/mL) | 4.08 ± 3.58 | 2.15 ± 2.12 | <0.001 | 3.72 ± 3.41 | 2.43 ± 2.59 | 0.009 | 3.54 ± 3.47 | 2.94 ± 2.96 | 0.499 |
| Plasma serpin A1 (µg/mL) | 1658.31 ± 845.39 | 1887.48 ± 1322.19 | 0.308 | 1819.04 ± 1278.03 | 1659.97 ± 765.84 | 0.697 | 1759.76 ± 797.16 | 1734.76 ± 1132.46 | 0.722 |
Significant findings (P < 0.05) are highlighted in bold fonts.
MBL, mannose-binding lectin; RBP4, retinol-binding protein 4; SAA1, serum amyloid A1.
Data are given as mean ± standard deviation.