Table 3.

Relationship of various acute phase proteins in plasma with the presence of intra-amniotic inflammation (IAI) and/or microbial invasion of the amniotic cavity (MIAC), acute histologic chorioamnionitis (HCA), and funisitis analyzed using multiple logistic regression.

Predictors	IAI and/or MIAC a		Acute HCAb		Funisitis c
	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Plasma hepcidin (ng/mL)	1.058 (1.015–1.102)	0.008
Plasma RBP4 (µg/mL)	0.891 (0.829–0.958)	0.002	0.935 (0.869–1.006)	0.072	0.875 (0.802–0.954)	0.003
Plasma SAA1 (µg/mL)	1.231 (1.097–1.382)	<0.001	1.113 (0.992–1.248)	0.068
Serum CRP (mg/dL)	2.020 (1.340–3.043)	0.001	1.835 (1.191–2.826)	0.006

Significant findings (P < 0.05) are highlighted in bold fonts.

OR, odds ratio; CI, confidence interval; RBP4, retinol-binding protein 4; SAA1, serum amyloid A1; CRP, C-reactive protein.

^a Adjustment for gestational age at sampling and parity.

^b Adjustment for gestational age at sampling, use of corticosteroids, and parity.

^c Adjustment for gestational age at sampling.