Fig. 8.

Chemical structure and mechanism of CB[n]. a Process of pharmacodynamics and pharmacokinetic detoxification. Reprinted with permission from ref 133.

Copyright 2020 Chemical Society Reviews. b The structures of M1, M2 and M3 CB[n]-type receptors. Reprinted with permission from ref 139. Copyright 2020 Chemistry. c Detoxification process of CB[7] complexed with PQ. Reprinted with permission from ref 145. Copyright 2019 Theranostics. d The structures of C2, C3 and C4 CB[n]-type receptors. Reprinted with permission from ref 140. Copyright 2019 Croatica Chemica Acta. e The AUC of asoxime-CB [7] is 3.2 times to that of oxime. Reprinted with permission from ref 142. Copyright 2021 Molecular Pharmaceutics