Table 1.

Types of cucurbit[n]uril in Supramolecular active-targeted therapy based on host–guest interactions

Cucurbit[n]uril	Targeted molecules		Reference
acyclic cucurbit[n]uril (CB[n])	organic compound	Alkylamines	[23]
		Spermidine	[26]
	Polymers	CPT-SS-TPP/CPT-mPEG	[114]
	medicines	Doxorubicin	[46]
		complexes of POD and VP-16	[53]
		NMBAs	[125]
		Fentanyl	[141]
Cucurbit[6]uril	organic compound	Alkylamines	[77]
		Spermidine (SP) /spermidine (SPD)	[98]
	Polymers	1,4-bis[2-(4-pyridyl)ethenyl]-benzene (BPEB) derivatives	[80]
		SP–folate (FA–SP)	[118]
	medicines	Doxorubicin	[47]
Cucurbit[7]uril	organic compound	4-(4-dimethylaminostyryl) quinoline (DSQ)	[92]
	Polymers	eight-arm polyethylene glycol (PEG8-Fc)	[29]
		[68 Ga]Ga-NOTA-PEG3-NMe2-Fc	[30]
		triphenylamine derivative (vinyl-pyridinium triphenylamines)	[61]
		hyaluronic acid (HA)−4-(4-bromophenyl)pyridin-1-ium bromide (BrBP)(HA-BrBP)	[69]
		Polyethylenimide (PEI)	[140]
	medicines	OxPt	[22]
		carboplatin/oxaliplatin	[25]
		Oximes	[31]
		Avidin	[93]
		paraquat (PQ)	[131]
		sorafenib (SO)	[134]
		Bedaquinoline (BDQ)	[135]
		trazodone (TZ)	[136]
		oxaliplatin (OxPt)	[140]
	Chloride	Asoxime	[127]
		nickelbutyl chloride (NC)	[137]
	Nanomaterials	GQDs-OH	[104]
	Photomolecule	diarylethene (DAE)	[87]
Cucurbit[8]uril	Medicines	acridine orange (AO) /oxaliplatin (OxPt)	[111]
		ketamine/morphine	[120]
	Polymers	Phe-Gly-Gly (FGG)	[37]
		Pt·pentapeptides Phe-(Gly)3-Cys	[38]
		dithienylethene derivative (DTE-MPBT)	[56]
		triphenylamine derivative (vinyl-pyridinium triphenylamines)	[61]
		cyanogenic astragalus derivatives	[73]
		diarylethene phenyl pyridine derivatives (DTE-TP)	[68]
		hyaluronic acid (HA)−4-(4-bromophenyl)pyridin-1-ium bromide (BrBP)(HA-BrBP)	[69]
		HA-CD/G	[81]
		tris-bipyridine derivative (1) and azobenzene quaternary ammonium salt (E-2)	[117]
	Nanomaterials	gold nanorods(GNR)	[86]
	Tubulin	microtubules (MTs)	[40]