Table 2.
Comparison of laboratory values among study groups
| Variables | Study Group (n = 31) | Obese (n = 11) | Obese + NAFLD (n = 20) | P-value | |
|---|---|---|---|---|---|
| ALT (IU/L, Median, IQR) | 25 (17–38) | 16 (14–22) | 30 (21.25–54.25) | 0.001 a | |
| CRP (mg/dL, Median, IQR) | 5 (4–7) | 5 (3–7) | 6 (4–7) | 0.416a | |
| Glucose (mmol/L, Median, IQR) | 4.5 (4.2–5.1) | 4.5 (4.2–5.4) | 4.56 (3.9–5.1) | 0.573a | |
| HOMA-IR (Median, IQR) | 2.4 (1.77–5.75) | 2.24 (1.42–4.1) | 2.50 (2-6.04) | 0.264a | |
| HOMA-IR subgroup (N, %) | 1.000b | ||||
| < 2.5 | 17 (54.9%) | 6 (19.4%) | 11 (35.5%) | ||
| > 2.5 | 14 (45.1%) | 5 (16.1%) | 9 (29%) | ||
| HbA1c (%, Median, IQR) | 5.5 (5.3–5.7) | 5.5 (5.2–5.6) | 5.5 (5.4–5.7) | 0.670a | |
| Cholesterol (mmol/L, Median, IQR) | 8.3 (7.6–9.3) | 8.9 (8.4–9.6) | 7.8 (7.5-9) | 0.083a | |
| Triglyceride (mmol/L, Median, IQR) | 6.4 (4.5–8.1) | 6.33 (4-7.5) | 6.5 (5.1–8.8) | 0.167a | |
| AST/ALT (N, %) | 0.502b | ||||
| < 1 | 14 (45.2%) | 4 (12.9%) | 10 (32.3%) | ||
| > 1 | 17 (54.8%) | 7 (22.5%) | 10 (32.3%) |
a: Mann-Whitney U Test; b: Fisher’s Exact Test
ALT: Alanine Aminotransferase, CRP: C-Reactive Protein, dL: Desiliter, IU: International Unit, IQR: Interquartile Range, L: Liter, mg: miligram, mmol: Milimol, NAFLD: Non-Alcoholic Fatty Liver Disease
All percentages were calculated based on the obese patient population (N = 31)
All p-values less than 0.05 was bold