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. 2024 Dec 23;30:267. doi: 10.1186/s10020-024-01018-z

Fig. 8.

Fig. 8

Upregulation of ANXA8 alleviates the inhibitory effect of RBM15 downregulation on NSCLC cells. A549 cells were transfected with oe-ANXA8, with oe-NC transfection as the negative control. A: The expression of ANXA8 was detected by RT-qPCR, with oe-NC used as control, N = 3; the comparison between two groups in panel A was analyzed using t-test. B: The expression of ANXA8 was detected by Western blot assay, with si-RBM15-3 + oe-NC used as control, N = 3; the comparison among multiple groups in panel B was analyzed using one-way ANOVA, followed by Tukey's multiple comparisons test. C: Cell proliferation was assessed by CCK-8 assay, with si-RBM15-3 + oe-NC used as control, N = 3; the comparison among multiple groups in panel C was analyzed using two-way ANOVA, followed by Tukey's multiple comparisons test. D: Cell proliferation was detected by colony formation assay, E: Cell invasion and migration were evaluated by Transwell assay, with si-RBM15-3 + oe-NC used as control, N = 3; the comparison among multiple groups in panels D and E was analyzed using one-way ANOVA, followed by Tukey's multiple comparisons test. The data were presented as mean ± standard deviation. ** p < 0.01