Table 3.
Correlation between IL-6 gene rs1800795(G-174C) genotype (CC) and RA across different ethnicities.
| Ethnicity | Number of studies included | Sample size | RA group(n/total) | CG (n/total) | Heterogeneity (I2) | OR [95%CI] | P |
|---|---|---|---|---|---|---|---|
| Asian | 4 | 2775 | 19/1278 | 6/1497 | 34 % | 2.85 [0.73, 11.04] | 0.13 |
| European | 6 | 2691 | 1791297 | 165/1394 | 31 % | 1.24 [0.92, 1.66] | 0.16 |
| Caucasian | 2 | 570 | 25/227 | 35/343 | 14 % | 1.08 [0.57,2.03] | 0.82 |
| Southeast Asian | 3 | 627 | 21/283 | 1/344 | 0 | 15.23 [3.53,65.67] | 0.0003 |
| Mixed | 3 | 1186 | 61/583 | 86/603 | 0 | 0.81 [0.57, 1.16] | 0.25 |