Fig. 4.

The proposed methodology effectively detects the diverse heterogeneity of endocrine cell groups, including single cells. The bar graph illustrates the mean and standard deviation of the number of endocrine cell groups per pancreas slide categorized by size. The endocrine cell groups vary in size ranging from single endocrine cells to endocrine cell groups. (A) Shows the count of the endocrine cell groups per area (endocrine cell group size: 0–2000 μm²), (B) shows the count of endocrine cell groups per area (endocrine cell group size: 2000–20,000 μm²).