Table 4.
Analyses stratified according to genotype for the relationship between birth weight and risk factors for CVD and DM-2
| Wild type | Variant carrier | |||
| Risk factor | β | 95% CI | β | 95% CI |
| BMI (kg/m2) | 0.475 | [-0.312; 1.262] | 0.777 | [-0.835; 2.338] |
| Fat mass (kg) | -0.217 | [-1.337; 0.904] | -1.929* | [-3.742; -0.116] |
| Fat free mass (kg) | 0.780 | [-0.212; 1.722] | 0.473 | [-0.897; 1.844] |
| Waist circumference (cm) | -1.380 | [-2.822; 0.061] | 0.040 | [-2.588; 2.668] |
| Waist-hip ratio | 0.002 | [-0.016; 0.021] | 0.021 | [-0.015; 0.057] |
| Systolic blood pressure (mmHg) | -1.497 | [-4.265; 1.272] | -8.038* | [0.014; -14.391] |
| Diastolic blood pressure (mmHg) | -0.599 | [-2.553; 1.355] | -5.073** | [-8.845; -1.301] |
| LDL cholesterol (mmol/l) | -0.138 | [-0.369; 0.093] | -0.076 | [-0.491; 0.339] |
| Resting heart rate (b/min) | 2.540 | [-0.865; 5.946] | -1.995 | [-8.277; 4.286] |
| Carotid intima-media thickness (mm)‡ | 0.010 | [-0.017; 0.036] | 0.020 | [-0.035; 0.075] |
| Glycated hemoglobin (%) | -0.019 | [-0.138; 0.101] | -0.025 | [-0.207; 0.157] |
Data is presented as regression coefficients (β) and their corresponding 95% confidence intervals (CI)
CVD – cardiovascular disease; DM-2 – type 2 diabetes mellitus
Models were adjusted for gender and adult body weight * p < 0.05 ** p < 0.01
‡ also adjusted for systolic and diastolic blood pressure