. 2024 Dec 23;16(4):1867–1875. doi: 10.1039/d4sc05558f

Table 1. Optimization of the reaction conditions^a.


Entry	Solvent	Yield^b (%)
1 ^c	CH ₃ CN	95
2	CH₃OH	87
3	EtOAc	62
4	Acetone	75
5	THF	18
6	Cyclohexane	22
7	DMSO	Trace
8	DMF	21
9	Toluene	24
10	CH₂Cl₂	n.d.
11	CH₃CN/H₂O (4/1)	72
12	CH₃CN/H₂O (1/4)	16

Reaction conditions: 1a (0.3 mmol) in solvent (15 mL) with γ-ray radiation (dose rate: 110 Gy min⁻¹, measured using a Fricke dosimeter) at room temperature and under an air atmosphere for 15 h.

Determined by gas chromatography-mass spectrometry (GC-MS) using 1,3,5-trimethoxybenzene as the internal standard.

The optimized reaction condition. n.d. = no detected.

Table 1. Optimization of the reaction conditionsa.

Table 1. Optimization of the reaction conditions^a.