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. 2005 Jun 17;5:69. doi: 10.1186/1471-2458-5-69

Table 3.

Odds ratios (95% confidence interval) of occurrence of Down syndrome Czech Republic, 1994–98

Crude 95% CI Fully adjusted* 95% CI
Lower Upper Lower Upper
Sex of infants
Boy 1 1
Girl 0.79 0.61 1.01 0.67 0.51 0.89

Education of mother
Primary 0.84 0.51 1.39 1.03 0.57 1.86
Vocational 0.88 0.58 1.34 1.06 0.66 1.70
Secondary 0.76 0.49 1.17 0.85 0.53 1.36
University 1 1

P for trend 0.98 0.44

Maternal age
-19 1 1
20–22 1.31 0.76 2.25 0.89 0.46 1.69
23–25 1.12 0.64 1.93 0.67 0.33 1.33
26–28 1.28 0.72 2.25 0.76 0.37 1.60
29–31 1.44 0.79 2.62 0.61 0.27 1.41
32–34 2.56 1.39 4.69 1.31 0.57 3.03
35–37 2.68 1.32 5.45 1.39 0.55 3.56
38–40 2.96 1.23 7.13 1.00 0.28 3.52
41–43 8.99 3.54 22.82 4.61 1.38 15.40
44+ 46.65 17.10 127.25 11.26 2.14 59.36
Paternal age
-19 1 1
20–22 0.63 0.18 2.19 0.68 0.19 2.41
23–25 1.09 0.34 3.51 1.33 0.40 4.50
26–28 1.03 0.32 3.32 1.34 0.39 4.63
29–31 0.94 0.29 3.08 1.23 0.35 4.40
32–34 1.24 0.37 4.12 1.49 0.41 5.46
35–37 1.95 0.58 6.53 1.98 0.52 7.44
38–40 2.21 0.63 7.69 2.02 0.51 7.96
41–43 2.10 0.54 8.14 1.68 0.38 7.42
44+ 3.03 0.82 11.20 2.03 0.47 8.77

Note: * -Adjusted for all variables in the Table.